Unlock the Science of Wellbeing

Explore WellVine™ real food prebiotic’s impact on gut and metabolic health.

WellVine™ Symposium 2023

The second annual WellVine™ Symposium brought together some of the brightest minds in the realm of food science to explore the extraordinary potential of WellVine™ real food prebiotic to be the next billion dollar ingredient revolutionizing the dietary supplement and culinary landscape.

SPOTLIGHT PUBLICATION

Uncovering the promising role of grape pomace as a modulator of the gut microbiome: An in-depth review*

Date: October 6, 2023
Authors: Amanda J.G. Sinrod, Ishita M. Shah, Ece Surek, and Daniela Barile
Journal: Heliyon

Spotlight Publications

Chardonnay Marc as a New Model for Upcycled Co-products in the Food Industry: Concentration of Diverse Natural Products Chemistry for Consumer Health and Sensory BenefitsDate:

Date: November 21, 2022
Authors: Roberta R. Holt, Daniela Barile, Selina C. Wang, John P. Munafo Jr., Torey Arvik, Xueqi Li, Fanny Lee, Carl L. Keen, Ilias Tagkopoulos, and Harold H. Schmitz
Journal: American Chemical Society

Gut Health And The Gut Microbiota

Chardonnay grape seed flour supplemented diets alter intestinal microbiota in diet-induced obese mice

Date:June 27, 2017
Authors: Kun-Ho Seo, Dong-Hyeon Kim, Dana Jeong, Wallace Yokoyama, and Hyunsook Kim
Journal: Journal of Food Biochemistry

Gut Health And The Gut Microbiota

Modulation of the Intestinal Microbiota Is Associated with Lower Plasma Cholesterol and Weight Gain in Hamsters Fed Chardonnay Grape Seed Flour

Date: June 27, 2017
Authors: Kun-Ho Seo, Dong-Hyeon Kim, Dana Jeong, Wallace Yokoyama, and Hyunsook Kim
Journal:Journal of Food Biochemistry

Oligosaccharide Research

Coupling an ion chromatography to high resolution mass spectrometry (IC-MS) for the discovery of potentially prebiotic oligosaccharides in Chardonnay grape marc

Date: January 2023
Authors: Tian Tian, Neil Rumachik, Amanda J.G. Sinrod, Daniela Barile, and Yan Liu
Journal: Journal of Chromatography B

Oligosaccharide Research

A second life for wine grapes: Discovering potentially bioactive oligosaccharides and phenolics in chardonnay marc and its processing fractions

Date: June 2021
Authors: Amanda J.G. Sinrod, Xueqi Li, Mrittika Bhattacharya, Bruna Paviani, Selina C. Wang, and Daniela Barile
Journal: LWT

Flavor Chemistry Research

Contribution of Key Odorants from Skins, Seeds, and Stems to the Aroma of Chardonnay Marc: A Valuable Coproduct of the Wine Industry

Date:October 12, 2023
Authors: Sarah Warner, Danielle M. Trudelle, Thien H. Nguyen, and John P. Munafo Jr.
Journal: Journal of Agricultural and Food Chemistry

Flavor Chemistry Research

Characterization of Key Odorants in Chardonnay Seeds

Date: December 13, 2022
Authors: Sarah Warner and John P. Munafo Jr.
Journal: Journal of Agricultural and Food Chemistry

Flavor Chemistry Research

Characterization of Odorants in Chardonnay Marc Skins

Date: October 8, 2021
Authors: Melissa Dein, Andrew Moore, Casey Ricketts, Chelsea Huynh, and John P. Munafo Jr
Journal: Journal of Agricultural and Food Chemistry

Upcycling

Upcycling flavanol‐rich Chardonnay and Pinot noir grape thinned clusters as potentially functional food ingredients in cocoa‐based products*

Date:April 4, 2023
Authors:Xueqi Li and Selina C. Wang
Journal:Food Science and Nutrition

Upcycling

Chardonnay Marc as a New Model for Upcycled Co-products in the Food Industry: Concentration of Diverse Natural Products Chemistry for Consumer Health and Sensory Benefits

Date: November 21, 2022
Authors: Roberta R. Holt, Daniela Barile, Selina C. Wang, John P. Munafo Jr., Torey Arvik, Xueqi Li, Fanny Lee, Carl L. Keen, Ilias Tagkopoulos, and Harold H. Schmitz
Journal: Journal of Agricultural and Food Chemistry

Cardiometabolic Health Research

Chardonnay Grape Marc Powder Supplementation May Increase Insulin Sensitivity in Obese and Overweight Men and Women

Date: June 2021
Authors
: Fanny Lee, Leslie Woodhouse, Torey Arvik, & Nancy Keim
Journal: Nutrition 2021 abstract presentation

Cardiometabolic Health Research

Evaluating Postprandial Lipid Response Following Chardonnay Grape Marc Powder Supplementation

Date: June 2020
Authors: Fanny Lee, Sridevi Krishnan, Aneeta Vedula, Torey Arvik, Paul Davis and Nancy Keim
Journal: Nutrition 2020 abstract presentation

Cardiometabolic Health Research

Identification of Differential, Health-Related Compounds in Chardonnay Marc through Network-Based Meta-Analysis

Date: June 2020
Authors: Simmons et al.
Journal: Nutrition 2020 abstract presentation

Cardiometabolic Health Research

The effect of polyphenol-rich chardonnay seed supplements on peripheral endothelial function

Date: February 17, 2020
Authors: Michel T. Corban, Robert Jay Widmer, Rebecca Cilluffo, Makinzee A. Kazeck, Ryan J. Lennon, Lilach O. Lerman & Amir Lerman
Journal: European Journal of Nutrition

Cardiometabolic Health Research

Chardonnay Grape Seed Flour Ameliorates Hepatic Steatosis and Insulin Resistance via Altered Hepatic Gene Expression for Oxidative Stress, Inflammation, and Lipid and Ceramide Synthesis in Diet-Induced Obese Mice*

Date: December 15, 2016
Authors: Kun-Ho Seo, Glenn E. Bartley, Christina Tam, Hong-Seok Kim, Dong-Hyeon Kim, Jung-Whan Chon, Hyunsook Kim and Wallace Yokoyama
Journal: PLOS One

Cardiometabolic Health Research

Flavonoid-rich Chardonnay grape seed flour supplementation ameliorates diet-induced visceral adiposity, insulin resistance, and glucose intolerance via altered adipose tissue gene expression

Date:August 2015
Authors: Kun-Ho Seo, Hyunsook Kim, Jung-Whan Chon, Dong-Hyeon Kim, Seung-Yeol Nah, Torey Arvik, and Wallace Yokoyama
Journal: Journal of Functional Foods

Cardiometabolic Health Research

Dietary Supplementation of Chardonnay Grape Seed Flour Reduces Plasma Cholesterol Concentration, Hepatic Steatosis, and Abdominal Fat Content in High-Fat Diet-Induced Obese Hamsters

Date: February 11, 2014
Authors: Hyunsook Kim, Glenn E. Bartley, Torey Arvik, Rebecca Lipson, Seung-Yeol Nah, Kunho Seo, and Wallace Yokoyama
Journal: Journal of Agricultural and Food Chemistry

Cardiometabolic Health Research

Chardonnay Grape Marc Powder Supplementation Decreases Acute Feelings of Hunger

Date: July 2023
Authors: Fanny Lee and Nancy Keim
Journal: Nutrition 2023 abstract presentation

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