Whole Fruit. Serious Science.
Explore the research behind WellVine’s whole-fruit prebiotic support for gut and metabolic health.
WellVine™ Symposium 2023 Video
The second annual WellVine Symposium brought together leading food scientists to explore WellVine’s distinctive combination of diverse prebiotic oligosaccharides and phenolics and its potential to help shape the future of functional foods, dietary supplements, and culinary innovation.
FEATURED GUT MICROBIOME REVIEW
Uncovering the promising role of grape pomace as a modulator of the gut microbiome: An in-depth review*
Date: October 6, 2023
Authors: Amanda J.G. Sinrod, Ishita M. Shah, Ece Surek, and Daniela Barile
Journal: Heliyon
Foundational Whole-Fruit Research
Chardonnay Marc as a New Model for Upcycled Co-products in the Food Industry: Concentration of Diverse Natural Products Chemistry for Consumer Health and Sensory Benefits
Date: November 21, 2022
Authors: Roberta R. Holt, Daniela Barile, Selina C. Wang, John P. Munafo Jr., Torey Arvik, Xueqi Li, Fanny Lee, Carl L. Keen, Ilias Tagkopoulos, and Harold H. Schmitz
Journal: American Chemical Society
Gut Microbiota Research
Chardonnay grape seed flour supplemented diets alter intestinal microbiota in diet-induced obese mice
Date:June 27, 2017
Authors: Kun-Ho Seo, Dong-Hyeon Kim, Dana Jeong, Wallace Yokoyama, and Hyunsook Kim
Journal: Journal of Food Biochemistry
Gut Microbiota Research
Modulation of the Intestinal Microbiota Is Associated with Lower Plasma Cholesterol and Weight Gain in Hamsters Fed Chardonnay Grape Seed Flour
Date: June 27, 2017
Authors: Kun-Ho Seo, Dong-Hyeon Kim, Dana Jeong, Wallace Yokoyama, and Hyunsook Kim
Journal:Journal of Food Biochemistry
Prebiotic Oligosaccharide Research
Coupling an ion chromatography to high resolution mass spectrometry (IC-MS) for the discovery of potentially prebiotic oligosaccharides in Chardonnay grape marc
Date: January 2023
Authors: Tian Tian, Neil Rumachik, Amanda J.G. Sinrod, Daniela Barile, and Yan Liu
Journal: Journal of Chromatography B
Prebiotic Oligosaccharide Research
A second life for wine grapes: Discovering potentially bioactive oligosaccharides and phenolics in chardonnay marc and its processing fractions
Date: June 2021
Authors: Amanda J.G. Sinrod, Xueqi Li, Mrittika Bhattacharya, Bruna Paviani, Selina C. Wang, and Daniela Barile
Journal: LWT
Flavor Chemistry Research
Contribution of Key Odorants from Skins, Seeds, and Stems to the Aroma of Chardonnay Marc: A Valuable Coproduct of the Wine Industry
Date:October 12, 2023
Authors: Sarah Warner, Danielle M. Trudelle, Thien H. Nguyen, and John P. Munafo Jr.
Journal: Journal of Agricultural and Food Chemistry
Flavor Chemistry Research
Characterization of Key Odorants in Chardonnay Seeds
Date: December 13, 2022
Authors: Sarah Warner and John P. Munafo Jr.
Journal: Journal of Agricultural and Food Chemistry
Flavor Chemistry Research
Characterization of Odorants in Chardonnay Marc Skins
Date: October 8, 2021
Authors: Melissa Dein, Andrew Moore, Casey Ricketts, Chelsea Huynh, and John P. Munafo Jr
Journal: Journal of Agricultural and Food Chemistry
Upcycling and Whole-Fruit Value
Upcycling flavanol‐rich Chardonnay and Pinot noir grape thinned clusters as potentially functional food ingredients in cocoa‐based products*
Date:April 4, 2023
Authors:Xueqi Li and Selina C. Wang
Journal:Food Science and Nutrition
Upcycling and Whole-Fruit Value
Chardonnay Marc as a New Model for Upcycled Co-products in the Food Industry: Concentration of Diverse Natural Products Chemistry for Consumer Health and Sensory Benefits
Date: November 21, 2022
Authors: Roberta R. Holt, Daniela Barile, Selina C. Wang, John P. Munafo Jr., Torey Arvik, Xueqi Li, Fanny Lee, Carl L. Keen, Ilias Tagkopoulos, and Harold H. Schmitz
Journal: Journal of Agricultural and Food Chemistry
Cardiometabolic Health Research
Chardonnay Grape Marc Powder Supplementation May Increase Insulin Sensitivity in Obese and Overweight Men and Women
Date: June 2021
Authors: Fanny Lee, Leslie Woodhouse, Torey Arvik, & Nancy Keim
Journal: Nutrition 2021 abstract presentation
Cardiometabolic Health Research
Evaluating Postprandial Lipid Response Following Chardonnay Grape Marc Powder Supplementation
Date: June 2020
Authors: Fanny Lee, Sridevi Krishnan, Aneeta Vedula, Torey Arvik, Paul Davis and Nancy Keim
Journal: Nutrition 2020 abstract presentation
Cardiometabolic Health Research
Identification of Differential, Health-Related Compounds in Chardonnay Marc through Network-Based Meta-Analysis
Date: June 2020
Authors: Simmons et al.
Journal: Nutrition 2020 abstract presentation
Cardiometabolic Health Research
The effect of polyphenol-rich chardonnay seed supplements on peripheral endothelial function
Date: February 17, 2020
Authors: Michel T. Corban, Robert Jay Widmer, Rebecca Cilluffo, Makinzee A. Kazeck, Ryan J. Lennon, Lilach O. Lerman & Amir Lerman
Journal: European Journal of Nutrition
Cardiometabolic Health Research
Chardonnay Grape Seed Flour Ameliorates Hepatic Steatosis and Insulin Resistance via Altered Hepatic Gene Expression for Oxidative Stress, Inflammation, and Lipid and Ceramide Synthesis in Diet-Induced Obese Mice*
Date: December 15, 2016
Authors: Kun-Ho Seo, Glenn E. Bartley, Christina Tam, Hong-Seok Kim, Dong-Hyeon Kim, Jung-Whan Chon, Hyunsook Kim and Wallace Yokoyama
Journal: PLOS One
Cardiometabolic Health Research
Flavonoid-rich Chardonnay grape seed flour supplementation ameliorates diet-induced visceral adiposity, insulin resistance, and glucose intolerance via altered adipose tissue gene expression
Date:August 2015
Authors: Kun-Ho Seo, Hyunsook Kim, Jung-Whan Chon, Dong-Hyeon Kim, Seung-Yeol Nah, Torey Arvik, and Wallace Yokoyama
Journal: Journal of Functional Foods
Cardiometabolic Health Research
Dietary Supplementation of Chardonnay Grape Seed Flour Reduces Plasma Cholesterol Concentration, Hepatic Steatosis, and Abdominal Fat Content in High-Fat Diet-Induced Obese Hamsters
Date: February 11, 2014
Authors: Hyunsook Kim, Glenn E. Bartley, Torey Arvik, Rebecca Lipson, Seung-Yeol Nah, Kunho Seo, and Wallace Yokoyama
Journal: Journal of Agricultural and Food Chemistry
Cardiometabolic Health Research
Chardonnay Grape Marc Powder Supplementation Decreases Acute Feelings of Hunger
Date: July 2023
Authors: Fanny Lee and Nancy Keim
Journal: Nutrition 2023 abstract presentation
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